A seal of approval from one of these organizations helps you know that the product was properly manufactured, contains the listed ingredients, and does not include harmful levels of contaminants.
It does not, however, guarantee the product's safety or effectiveness. Make sure to read the label before you purchase any supplement. Look for supplements that have been quality tested by a third party. Lysine is an important amino acid that can be found in high-protein foods like meat, nuts, beans, and eggs.
It is also available as an oral supplement or topical ointment. Some research suggests that lysine may be helpful for treating certain conditions, such as cold sores and anxiety.
Before taking lysine, talk to your doctor about dosage and use. Some studies have shown that lysine has a small impact on glucose levels. Lysine is consumed naturally in meat beef, pork, poultry , cheese, certain fish, eggs, beans, legumes, and dairy products. Most people get enough lysine in their diets, but those who do not may experience fatigue, nausea, dizziness, loss of appetite, agitation, bloodshot eyes, anemia, and reproductive challenges.
Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life. Medicinal uses of l-lysine: past and future. Int J Res Pharm Sci. Mailoo VJ, Rampes S.
Lysine for herpes simplex prophylaxis: a review of the evidence. Integr Med. Interventions for prevention of herpes simplex labialis cold sores on the lips. Cochrane Database Syst Re v. Safety and effectiveness of an L-lysine, zinc, and herbal-based product on the treatment of facial and circumoral herpes.
Altern Med Rev. Camfield DA. Nutritional-based nutraceuticals in the treatment of anxiety. Springer; Supplementing a low-protein diet with dibasic amino acids increases urinary calcium excretion in young women.
J Nutr. Lysine supply is a critical factor in achieving sustainable global protein economy. Front Sust Food Syst. Quality certification programs for dietary supplements. J Acad Nutr Diet. Lysine ingestion markedly attenuates the glucose response to ingested glucose without a change in insulin response. The American Journal of Clinical Nutrition. Many people consume enough lysine in their diet. But some — athletes or vegans specifically — may need to consume more.
In order to replicate in the body, herpes simplex needs a steady source of arginine. This amino acid converts into nitric oxide within your body, a chemical necessary to expand blood vessels and improve blood flow. Lysine is thought to interfere with arginine being absorbed into your intestine , making the amino acid unavailable for the virus. So even if it may not cure a cold sore infection, lysine can help slow or prevent the HSV-1 replication process.
In addition, older research suggests that lysine may reduce the number of occurrences of this infection and decrease healing time. For example, a small study from showed that lysine sped up the healing process for 87 percent of participants, shortening the average time from 21 days to 6 days for these people.
To treat a cold sore infection, apply lysine cream to the affected area every two hours for 11 days. To manage cold sore infections, the recommended dosage for oral supplements is 1 gram three times daily.
To help prevent them, the dosage is 1 gram daily. If you see no improvement in your condition, discuss dosages and alternative treatment with your doctor. If you begin to experience worsening symptoms, stop treatment immediately. Doses of up to 3g per day are well tolerated; however, higher doses g per day can cause gastrointestinal disturbances, including nausea, abdominal cramps and diarrhea. Rio de Janeiro: Guanabara Koogan; Lysine kinetics at graded lysine intakes in young men.
Am J Clin Nutr. Lysine requirement of adult males is not affected by decreasing dietary protein. Prophylaxis against herpes simplex virus reactivation in patients with facial burns: a-potential role for l-lysine.
J Burn Care Res. Effect of L-Lysine-a-oxidase on reproduction of herpes simplex type 1 virus in vitro. Vopr Med Khim. Antiherpetic Activity of L-Lysine-alpha-oxidase in different dosage forms. Antibiot Khimioter. Success of L-lysine therapy in frequently recurrent Herpes simplex infection. Treatment and prophylaxis. Use of lysine in treating recurrent oral Herpes simplex infections.
Gen Dent. A multicentered study of lysine therapy in Herpes simplex infection. Lysine prophylaxis in recurrent Herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol. Relation of arginine-lysine antagonism to Herpes simplex growth in tissue culture. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis.
The objective of this study was to show, through clinical observation, a significant effect on the annual incidence reduction of recurrent herpes in a 8-year follow up. The prospective study was conducted in a group of 12 individuals, being five males and seven females aged between 30 and 48 years old, suffering from recurrent herpes labialis lesions with manifestations ranging from over one or more episode per month to one or more every three months.
All members belonged to the same socio-economic and cultural class and they had never received any systemic therapy prior to the study.
Besides prescription treatments, some people have tried lysine for cold sores, as well as other natural cold sore remedies. But is lysine worth trying, and will it really help to prevent these sores? Lysine is one of nine essential amino acids, which are compounds that combine to form proteins, as the NIH notes.
Your body needs these to grow, repair itself and digest food. The human body doesn't produce these essential amino acids on its own, so instead, you get them from food or from taking supplements. Lysine, in particular, also plays a role in helping your body develop collagen and absorb calcium, and it aids in the production of carnitine, which may help to lower cholesterol levels, according to PennState Hershey Milton S.
Hershey Medical Center. Meat, cheese, eggs, beans especially soybeans and fenugreek are all good sources of lysine.
And while most people get an adequate amount of lysine from their diet, those who exercise a lot or those who follow a vegan diet and avoid beans might be lysine deficient. Lysine is occasionally promoted as a natural remedy for cold sores. The Mayo Clinic lists it as an alternative treatment option, available as either an oral supplement or a cream, and PennState Hershey Milton S. Hershey Medical Center notes that lysine supplements may potentially help to reduce the occurrence of cold sore outbreaks, though not all experts believe it works.
One theory on why lysine is thought to help reduce cold sore outbreaks is that the amino acid may interfere with the activity of arginine, another amino acid, and block herpes replication, according to an article in Clinical Advisor.
So far, studies focusing on lysine for cold sores in humans haven't drawn any firm conclusions.
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